Specialists said that homocysteine may help predict how skin changes with age. researchers showed that despite the impact of smoking and sun exposure on the skin aging genes, however, persons may have a greater impact. the specialists said that this pilot research may help find out the differences between large and small old gene age. And they showed that by understanding how to make large genes in age appear small and how to keep small genes that become large in age then can provide better advice for patients to take care of their skin. researchers will now look at the differences between how the genes in large and small skin age and how the diet in these genes. in the study, researchers give pregnant rat food waned folic acid which alters the expression genes responsible for hair color at birth. Poor diet caused a change in hair color from black to blonde at birth and all future generations. this study shows impact of diet on expression of genes significantly. the researchers said that following generations of studies based on genes may help determine not only which components might work better for specific types of skin but the intake person throughout life may affect the skin too.